PRDM11

Across TCGA patient cohorts, PRDM11 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,070 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRDM11-associated proteins across cancer lineages are SMC1A, VEZF1, and MTA1. Each is linked with PRDM11 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRDM11-to-partner and partner-to-PRDM11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDM11 versus SMC1A in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM11→partner) and Y-score (partner→PRDM11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC1A →	+0.336	+0.514	.001	.002	3	7
GBM	VEZF1 →	+0.377	+0.490	<.001	<.001	3	6
HNSC	MTA1 →	+0.435	+0.742	<.001	<.001	3	6
HNSC	SIN3A →	+0.239	+0.789	<.001	<.001	3	6
GBM	BRD3 →	+0.290	+0.567	<.001	<.001	3	6
GBM	EPS15_S221 →	-0.374	-0.485	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,070 associations by consensus.

PRDM11 vs SMC1A — GBM

Explore this scatter interactively →