PRDM11

Across TCGA cell cohorts, PRDM11 RNA expression is significantly associated with the RNA expression of many other genes, with 11,373 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PRDM11-associated genes across cancer lineages are NFATC3, CREBBP, and NAA40. Each is linked with PRDM11 in more than 12 cancer types. Because this analysis shows association rather than direction, both PRDM11-to-partner and partner-to-PRDM11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDM11 versus NFATC3 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM11→partner) and Y-score (partner→PRDM11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	NFATC3 →	+1.008	+1.214	.008	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	CREBBP →	+1.360	+1.173	<.001	<.001	3	13
BREAST	NAA40 →	+1.168	+0.978	<.001	<.001	3	12
BLOOD_Lymphoma	ZC3H4 →	+0.870	+0.615	<.001	<.001	3	12
LARGE_INTESTINE	SF1 →	+1.011	+0.888	<.001	<.001	2	13
UPPER_AERODIGESTIVE_TRACT	PCNX3 →	+0.952	+1.122	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,373 associations by consensus.

PRDM11 vs NFATC3 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →