PRB4

Across TCGA patient cohorts, PRB4 RNA expression is significantly associated with the RNA expression of many other genes, with 7,151 significant associations in total. LAML shows the largest number of these associations.

The most reproducible PRB4-associated genes across cancer lineages are PRB1, PRB2, and PRR4. Each is linked with PRB4 in more than 20 cancer types. Because this analysis shows association rather than direction, both PRB4-to-partner and partner-to-PRB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRB4 versus PRB1 in LAML, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRB4→partner) and Y-score (partner→PRB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	PRB1 →	+0.686	+1.139	<.001	<.001	3	21
SARC	PRB2 →	+0.678	+0.329	<.001	<.001	3	18
HNSC	PRR4 →	+1.059	+0.172	<.001	<.001	3	11
THYM	PRB3 →	+1.398	+0.750	<.001	<.001	3	10
THYM	PRH1 →	+0.938	+0.722	<.001	.007	1	11
LAML	LINC01252 →	+1.366	+1.025	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,151 associations by consensus.

PRB4 vs PRB1 — LAML

Explore this scatter interactively →