PRB4

Across TCGA patient cohorts, PRB4 protein abundance is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PRB4-associated genes across cancer lineages are GLCCI1, ZNF157, and PDK1. Each is linked with PRB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRB4-to-partner and partner-to-PRB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRB4 versus GLCCI1 in HNSC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRB4→partner) and Y-score (partner→PRB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GLCCI1 →	+2.368	+3.346	.007	.001	3	1
HNSC	ZNF157 →	-0.248	-2.757	.007	.002	3	1
HNSC	PDK1 →	+1.172	+2.680	.007	.003	3	1
HNSC	MAP3K19 →	+0.564	+2.814	.004	.008	3	1
HNSC	RNU6-605P →	+1.535	+3.247	.006	.005	3	1
HNSC	MIR646 →	+2.057	+2.680	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

PRB4 vs GLCCI1 — HNSC

Explore this scatter interactively →