PRB4

Across TCGA cell cohorts, PRB4 RNA expression is significantly associated with the RNA expression of many other genes, with 1,730 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRB4-associated genes across cancer lineages are OR5C1, OR52H1, and LCE1F. Each is linked with PRB4 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRB4-to-partner and partner-to-PRB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRB4 versus OR5C1 in LUNG_SCLC, with a Pearson correlation of 0.60.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRB4→partner) and Y-score (partner→PRB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR5C1 →	+0.044	+0.045	<.001	.001	3	4
STOMACH	OR52H1 →	+0.058	+0.072	.009	.002	3	3
SKIN	LCE1F →	+0.445	+0.014	<.001	.007	3	3
CNS	SLC13A1 →	+0.036	+0.091	.002	.003	3	3
BONE	RGS21 →	+0.284	+0.035	<.001	.003	3	2
STOMACH	TAS2R9 →	+0.051	+0.046	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,730 associations by consensus.

PRB4 vs OR5C1 — LUNG_SCLC

Explore this scatter interactively →