Across TCGA patient cohorts, PRAMEF7 mutation is significantly associated with the RNA expression of many other genes, with 67 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PRAMEF7-associated genes across cancer lineages are RNA5SP405, MIR6133, and HLA-Z. Each is linked with PRAMEF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRAMEF7-to-partner and partner-to-PRAMEF7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRAMEF7→partner) and Y-score (partner→PRAMEF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP405 →	+1.586	+6.582	<.001	.001	3	2
UCEC	MIR6133 →	+0.725	+4.982	.001	.009	3	1
SKCM	HLA-Z →	+0.602	+2.948	.003	.007	3	1
SKCM	SAPCD2P2 →	+0.019	+3.159	<.001	.008	3	1
SKCM	GOLGA2P6 →	+0.007	+4.411	<.001	.005	3	1
SKCM	LINC02434 →	+1.799	+3.935	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

Exploration

PRAMEF7 survival (RNA) · tumor vs normal (RNA) · all PRAMEF7 data types