Across TCGA pan-cancer cohorts, PRAMEF7 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PRAMEF7’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where PRAMEF7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PRAMEF7 is over-expressed in tumor.

LIHC and CHOL are the cancer types where PRAMEF7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PRAMEF7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.075	.029	2	view →
CHOL	All	All	+0.151	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: PRAMEF7 RNA expression & survival · all PRAMEF7 data types