Across TCGA patient cohorts, PPTC7 protein abundance is significantly associated with the RNA expression of many other genes, with 5,622 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PPTC7-associated genes across cancer lineages are TRA2B, PFKM, and CTSG. Each is linked with PPTC7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PPTC7-to-partner and partner-to-PPTC7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPTC7→partner) and Y-score (partner→PPTC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRA2B →	-0.419	-0.258	<.001	<.001	3	3
HNSC	PFKM →	+0.629	+0.249	<.001	<.001	3	3
CCRCC	CTSG →	-1.042	-0.360	<.001	<.001	3	2
BRCA	FAM83D →	-1.103	-0.297	<.001	<.001	3	2
BRCA	KIF20A →	-0.992	-0.312	<.001	<.001	3	2
BRCA	SMC4 →	-0.702	-0.283	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,622 associations by consensus.

Exploration

PPTC7 survival (RNA) · tumor vs normal (RNA) · all PPTC7 data types