PPP5C

Across TCGA patient cohorts, PPP5C RNA expression is significantly associated with the protein abundance of many other proteins, with 14,709 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP5C-associated proteins across cancer lineages are LIG1, PRMT1, and XRCC1. Each is linked with PPP5C in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP5C-to-partner and partner-to-PPP5C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP5C versus LIG1 in LUAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP5C→partner) and Y-score (partner→PPP5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LIG1 →	+0.426	+0.343	<.001	<.001	3	8
LUAD	PRMT1 →	+0.301	+0.380	<.001	<.001	3	7
GBM	XRCC1 →	+0.397	+0.609	<.001	<.001	3	7
GBM	SAE1 →	+0.366	+0.493	<.001	<.001	3	7
GBM	IRF2BP1 →	+0.369	+0.473	<.001	<.001	3	7
GBM	TRIM28 →	+0.372	+0.416	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,709 associations by consensus.

PPP5C vs LIG1 — LUAD

Explore this scatter interactively →