PPP4R1

Across TCGA patient cohorts, PPP4R1 mutation is significantly associated with the RNA expression of many other genes, with 3,813 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP4R1-associated genes across cancer lineages are RPS29P32, FAM204BP, and RN7SL654P. Each is linked with PPP4R1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP4R1-to-partner and partner-to-PPP4R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P32 grouped by PPP4R1-low versus PPP4R1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP4R1→partner) and Y-score (partner→PPP4R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS29P32 →	+0.294	+1.769	<.001	.002	3	3
COAD	FAM204BP →	+0.261	+2.516	.002	.007	3	3
LUSC	RN7SL654P →	+0.057	+4.520	.001	.004	3	3
LUAD	HNRNPDP2 →	+0.104	+7.930	<.001	.008	3	3
STAD	H3P46 →	+0.207	+3.646	.005	.009	3	3
UCEC	ADM →	+0.738	+1.283	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,813 associations by consensus.

RPS29P32 by PPP4R1 expression — UCEC

Explore this box plot interactively →