PPP3CB

Across TCGA patient cohorts, PPP3CB RNA expression is significantly associated with the protein abundance of many other proteins, with 16,012 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP3CB-associated proteins across cancer lineages are NHLRC2, RSL1D1, and AFG3L2. Each is linked with PPP3CB in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP3CB-to-partner and partner-to-PPP3CB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP3CB versus NHLRC2 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP3CB→partner) and Y-score (partner→PPP3CB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NHLRC2 →	+0.269	+0.633	<.001	<.001	3	5
BRCA	RSL1D1 →	-0.683	-0.588	<.001	<.001	3	5
OV	AFG3L2 →	-0.675	-0.516	<.001	<.001	3	5
COAD	MAP1A →	+0.394	+0.479	<.001	<.001	3	5
COAD	SIRT1 →	+0.436	+0.507	.006	.005	3	5
BRCA	ADO →	+0.200	+0.338	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,012 associations by consensus.

PPP3CB vs NHLRC2 — GBM

Explore this scatter interactively →