PPP3CB

Across TCGA patient cohorts, PPP3CB protein abundance is significantly associated with the RNA expression of many other genes, with 18,053 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP3CB-associated genes across cancer lineages are PRKCB, FLI1, and ZEB2. Each is linked with PPP3CB in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP3CB-to-partner and partner-to-PPP3CB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP3CB versus PRKCB in GBM, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP3CB→partner) and Y-score (partner→PPP3CB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRKCB →	+0.915	+0.446	<.001	<.001	3	8
LSCC	FLI1 →	+0.621	+0.260	<.001	<.001	3	7
COAD	ZEB2 →	+0.826	+0.279	<.001	<.001	3	7
BRCA	CXCL12 →	+1.164	+0.268	<.001	<.001	3	6
UCEC	CNRIP1 →	+0.964	+0.373	<.001	<.001	3	6
GBM	CD22 →	+1.047	+0.437	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,053 associations by consensus.

PPP3CB vs PRKCB — GBM

Explore this scatter interactively →