PPP3CB

Across TCGA cell cohorts, PPP3CB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,724 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP3CB-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Regulation of chromosome segregation, and Regulation of sister chromatid segregation. Each is linked with PPP3CB in more than 15 cancer types. Because this analysis shows association rather than direction, both PPP3CB-to-partner and partner-to-PPP3CB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by PPP3CB-low versus PPP3CB-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP3CB→partner) and Y-score (partner→PPP3CB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.117	+0.723	<.001	<.001	3	16
URINARY_TRACT	Regulation of chromosome segregation →	+0.105	+0.891	<.001	<.001	3	15
URINARY_TRACT	Regulation of sister chromatid segregation →	+0.102	+0.910	<.001	<.001	3	14
LIVER	Negative regulation of chromosome segregation →	+0.143	+1.233	<.001	<.001	3	14
PANCREAS	Mitotic spindle assembly →	+0.089	+0.726	<.001	<.001	3	14
OVARY	DAMP biosynthetic process →	+0.112	+0.968	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,724 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by PPP3CB expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →