PPP2R5E

Across TCGA patient cohorts, PPP2R5E RNA expression is significantly associated with the protein abundance of many other proteins, with 15,804 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP2R5E-associated proteins across cancer lineages are MTHFD1, NAA35, and PPP4R3A. Each is linked with PPP2R5E in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP2R5E-to-partner and partner-to-PPP2R5E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R5E versus MTHFD1 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5E→partner) and Y-score (partner→PPP2R5E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MTHFD1 →	+0.423	+0.456	<.001	<.001	3	8
GBM	NAA35 →	+0.212	+0.388	<.001	<.001	3	7
GBM	PPP4R3A →	+0.265	+0.399	<.001	<.001	3	6
LSCC	SSRP1 →	+0.537	+0.596	<.001	<.001	3	6
GBM	SUPT16H →	+0.369	+0.396	<.001	<.001	3	6
LSCC	AHSA1 →	+0.259	+0.364	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,804 associations by consensus.

PPP2R5E vs MTHFD1 — OV

Explore this scatter interactively →