PPP2R5D

Across TCGA patient cohorts, PPP2R5D RNA expression is significantly associated with the protein abundance of many other proteins, with 16,725 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R5D-associated proteins across cancer lineages are XPO5, TBCC, and SMC4. Each is linked with PPP2R5D in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP2R5D-to-partner and partner-to-PPP2R5D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R5D versus XPO5 in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5D→partner) and Y-score (partner→PPP2R5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XPO5 →	+0.724	+0.703	<.001	<.001	3	8
OV	TBCC →	+0.401	+0.638	<.001	<.001	3	8
GBM	SMC4 →	+0.437	+0.238	<.001	.001	3	6
GBM	SPC24 →	+0.634	+0.372	<.001	<.001	3	6
LSCC	CMTR1 →	+0.313	+0.466	<.001	<.001	3	6
LSCC	GTF3C4 →	+0.308	+0.462	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,725 associations by consensus.

PPP2R5D vs XPO5 — LSCC

Explore this scatter interactively →