PPP2R5C

Across TCGA patient cohorts, PPP2R5C protein abundance is significantly associated with the RNA expression of many other genes, with 11,674 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R5C-associated genes across cancer lineages are WDR20, EIF5, and WDR25. Each is linked with PPP2R5C in more than 5 cancer types. Because this analysis shows association rather than direction, both PPP2R5C-to-partner and partner-to-PPP2R5C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R5C versus WDR20 in LUAD, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5C→partner) and Y-score (partner→PPP2R5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	WDR20 →	+0.398	+0.228	<.001	<.001	3	6
HNSC	EIF5 →	+0.465	+0.199	.003	<.001	3	5
COAD	WDR25 →	+0.429	+0.256	<.001	.001	3	5
HNSC	GLRX5 →	+0.503	+0.229	.004	<.001	3	5
LUAD	DDX24 →	+0.403	+0.219	<.001	<.001	3	5
LSCC	RCOR1 →	+0.630	+0.279	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,674 associations by consensus.

PPP2R5C vs WDR20 — LUAD

Explore this scatter interactively →