PPP2R3B

Across TCGA patient cohorts, PPP2R3B protein abundance is significantly associated with the RNA expression of many other genes, with 4,967 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R3B-associated genes across cancer lineages are TOR4A, FOXP1, and DPYSL4. Each is linked with PPP2R3B in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP2R3B-to-partner and partner-to-PPP2R3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R3B versus TOR4A in LSCC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R3B→partner) and Y-score (partner→PPP2R3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TOR4A →	-0.831	-0.421	<.001	<.001	3	3
UCEC	FOXP1 →	-0.632	-0.640	.003	.006	3	2
UCEC	DPYSL4 →	+1.325	+0.713	<.001	.001	3	2
UCEC	INKA2 →	+0.754	+0.700	.002	.008	3	2
UCEC	RNU6-177P →	-0.987	-0.731	.003	<.001	3	2
UCEC	GEMIN8P4 →	+1.106	+0.636	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,967 associations by consensus.

PPP2R3B vs TOR4A — LSCC

Explore this scatter interactively →