gem nuclear organelle associated protein 8 pseudogene 4Genealiases: []
Q-omics provides the consensus-scored GEMIN8P4 profile across patient tissues and cancer cell-line models. GEMIN8P4 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, GEMIN8P4 is differentially expressed in 16, with the highest sampling consensus in KICH. Additionally, GEMIN8P4 RNA expression shows 17,838 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight KIRC, KICH, and ACC as cancer lineages where GEMIN8P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GEMIN8P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GEMIN8P4 survival associations across molecular data types. GEMIN8P4 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GEMIN8P4 RNA expression–survival associations across cancer types. High GEMIN8P4 expression shows unfavorable associations in KIRC, UCEC, LIHC, LGG, KIRP and ACC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for GEMIN8P4 RNA expression.
This table summarizes GEMIN8P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 16. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for GEMIN8P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GEMIN8P4 shows lower tumor expression in KICH, THCA and KIRC and higher tumor expression in BLCA, LUSC and LUAD. The KICH box plot shows higher GEMIN8P4 RNA expression in normal versus tumor tissue (log2 FC = −1.772, t-test p < 0.001).
This table shows molecular features associated with GEMIN8P4 in patient tissues and cancer cell lines. In patient samples, GEMIN8P4 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
