PPP2R2D

Across TCGA patient cohorts, PPP2R2D RNA expression is significantly associated with the protein abundance of many other proteins, with 16,688 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R2D-associated proteins across cancer lineages are CTBP2, PWWP2B, and TRUB1. Each is linked with PPP2R2D in more than 7 cancer types. Because this analysis shows association rather than direction, both PPP2R2D-to-partner and partner-to-PPP2R2D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R2D versus CTBP2 in OV, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2D→partner) and Y-score (partner→PPP2R2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CTBP2 →	+0.378	+0.431	.003	<.001	2	8
LSCC	PWWP2B →	+0.367	+0.446	<.001	<.001	3	5
LSCC	TRUB1 →	+0.266	+0.373	<.001	<.001	3	5
GBM	NHLRC2 →	+0.240	+0.398	<.001	<.001	3	5
LSCC	RNF20 →	+0.203	+0.339	<.001	<.001	3	5
OV	BTAF1 →	+0.207	+0.365	.005	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,688 associations by consensus.

PPP2R2D vs CTBP2 — OV

Explore this scatter interactively →