PPP2R2D

Across TCGA patient cohorts, PPP2R2D protein abundance is significantly associated with the RNA expression of many other genes, with 14,902 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R2D-associated genes across cancer lineages are BBIP1, GINS1, and CENPI. Each is linked with PPP2R2D in more than 5 cancer types. Because this analysis shows association rather than direction, both PPP2R2D-to-partner and partner-to-PPP2R2D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R2D versus BBIP1 in GBM, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2D→partner) and Y-score (partner→PPP2R2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BBIP1 →	+0.416	+0.388	<.001	<.001	3	6
LUAD	GINS1 →	-0.789	-0.165	<.001	<.001	3	5
LUAD	CENPI →	-0.872	-0.192	<.001	<.001	3	5
UCEC	ASF1B →	-0.920	-0.267	.005	.002	3	5
LSCC	EZH2 →	-0.990	-0.298	<.001	<.001	3	5
GBM	ASPA →	+0.757	+0.302	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,902 associations by consensus.

PPP2R2D vs BBIP1 — GBM

Explore this scatter interactively →