PPP2R2D

Across TCGA cell cohorts, PPP2R2D RNA expression is significantly associated with the go_rna of many other GO terms, with 3,283 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP2R2D-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Negative regulation of gene expression, epigenetic, and Microtubule nucleation. Each is linked with PPP2R2D in more than 14 cancer types. Because this analysis shows association rather than direction, both PPP2R2D-to-partner and partner-to-PPP2R2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by PPP2R2D-low versus PPP2R2D-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R2D→partner) and Y-score (partner→PPP2R2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.108	+0.983	<.001	<.001	3	15
BONE	Negative regulation of gene expression, epigenetic →	+0.082	+0.655	.001	<.001	3	13
BONE	Microtubule nucleation →	+0.159	+0.608	<.001	<.001	3	12
BONE	Establishment of mitotic spindle localization →	+0.128	+0.623	<.001	<.001	3	12
BONE	Positive regulation of DNA metabolic process →	+0.078	+0.527	.001	.001	3	12
BLOOD_Lymphoma	Protein localization to chromosome →	+0.070	+0.589	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,283 associations by consensus.

Viral translational termination-reinitiation by PPP2R2D expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →