PPP2R1B

Across TCGA patient cohorts, PPP2R1B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,188 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP2R1B-associated proteins across cancer lineages are ST14, CUL5, and ARHGEF12. Each is linked with PPP2R1B in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP2R1B-to-partner and partner-to-PPP2R1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R1B versus ST14 in LUAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R1B→partner) and Y-score (partner→PPP2R1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ST14 →	+0.368	+0.445	<.001	<.001	3	5
HNSC	CUL5 →	+0.277	+0.593	<.001	<.001	3	5
HNSC	ARHGEF12 →	+0.296	+0.822	<.001	<.001	3	4
HNSC	UBE4A →	+0.335	+0.644	<.001	<.001	3	4
BRCA	DERL1 →	-0.564	-0.491	<.001	<.001	3	4
HNSC	CWF19L2 →	+0.299	+0.924	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,188 associations by consensus.

PPP2R1B vs ST14 — LUAD

Explore this scatter interactively →