PPP2R1B

Across TCGA patient cohorts, PPP2R1B protein abundance is significantly associated with the RNA expression of many other genes, with 11,047 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP2R1B-associated genes across cancer lineages are MIR100HG, SLC27A2, and EI24. Each is linked with PPP2R1B in more than 5 cancer types. Because this analysis shows association rather than direction, both PPP2R1B-to-partner and partner-to-PPP2R1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R1B versus MIR100HG in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R1B→partner) and Y-score (partner→PPP2R1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MIR100HG →	-0.995	-0.502	.003	<.001	3	6
UCEC	SLC27A2 →	+1.321	+0.388	<.001	<.001	3	5
HNSC	EI24 →	+0.685	+0.550	<.001	<.001	3	5
BRCA	DLAT →	+0.634	+0.399	<.001	<.001	3	5
BRCA	GPT2 →	+0.941	+0.303	.001	.004	3	5
UCEC	NAP1L3 →	-0.657	-0.250	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,047 associations by consensus.

PPP2R1B vs MIR100HG — OV

Explore this scatter interactively →