PPP2R1B

Across TCGA cell cohorts, PPP2R1B RNA expression is significantly associated with the RNA expression of many other genes, with 10,672 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP2R1B-associated genes across cancer lineages are SIK2, ZW10, and DLAT. Each is linked with PPP2R1B in more than 19 cancer types. Because this analysis shows association rather than direction, both PPP2R1B-to-partner and partner-to-PPP2R1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R1B versus SIK2 in STOMACH, with a Pearson correlation of 0.52.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R1B→partner) and Y-score (partner→PPP2R1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SIK2 →	+0.955	+0.864	<.001	<.001	2	20
KIDNEY	ZW10 →	+1.041	+0.917	<.001	<.001	3	18
BLOOD_Lymphoma	DLAT →	+1.023	+0.890	<.001	<.001	3	17
OVARY	CUL5 →	+1.135	+1.275	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	UBE4A →	+1.187	+1.027	<.001	<.001	3	16
CNS	ALKBH8 →	+1.004	+0.860	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,672 associations by consensus.

PPP2R1B vs SIK2 — STOMACH

Explore this scatter interactively →