PPP2R1A

Across TCGA patient cohorts, PPP2R1A RNA expression is significantly associated with the protein abundance of many other proteins, with 13,716 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP2R1A-associated proteins across cancer lineages are TRIM28, NFIA, and UFL1. Each is linked with PPP2R1A in more than 5 cancer types. Because this analysis shows association rather than direction, both PPP2R1A-to-partner and partner-to-PPP2R1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP2R1A versus TRIM28 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R1A→partner) and Y-score (partner→PPP2R1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.311	+0.268	<.001	<.001	3	6
GBM	NFIA →	+0.361	+0.227	<.001	<.001	3	5
OV	UFL1 →	-0.304	-0.720	.001	<.001	3	5
BRCA	ARHGAP35 →	+0.349	+0.402	.001	<.001	2	5
GBM	FAM114A2 →	-0.187	-0.249	<.001	<.001	3	4
UCEC	MAP3K3_S250 →	-0.399	-0.847	.009	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,716 associations by consensus.

PPP2R1A vs TRIM28 — GBM

Explore this scatter interactively →