PPP1R7

Across TCGA patient cohorts, PPP1R7 protein abundance is significantly associated with the RNA expression of many other genes, with 13,607 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R7-associated genes across cancer lineages are CDCA4, CDC6, and RHBDD1. Each is linked with PPP1R7 in more than 5 cancer types. Because this analysis shows association rather than direction, both PPP1R7-to-partner and partner-to-PPP1R7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R7 versus CDCA4 in HNSC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R7→partner) and Y-score (partner→PPP1R7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CDCA4 →	-0.853	-0.140	<.001	<.001	3	6
LUAD	CDC6 →	-0.721	-0.167	.002	<.001	3	6
BRCA	RHBDD1 →	+0.551	+0.327	<.001	<.001	3	6
COAD	CAB39L →	+1.395	+0.239	<.001	<.001	3	6
PDAC	CPED1 →	+0.721	+0.222	<.001	<.001	3	6
HNSC	FAM83D →	-1.076	-0.171	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,607 associations by consensus.

PPP1R7 vs CDCA4 — HNSC

Explore this scatter interactively →