PPP1R7

Across TCGA patient cohorts, PPP1R7 mutation is significantly associated with the RNA expression of many other genes, with 390 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R7-associated genes across cancer lineages are RNA5SP346, MTND2P22, and MLLT10P2. Each is linked with PPP1R7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R7-to-partner and partner-to-PPP1R7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP346 grouped by PPP1R7-low versus PPP1R7-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R7→partner) and Y-score (partner→PPP1R7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP346 →	+0.312	+7.731	<.001	.009	3	3
BLCA	MTND2P22 →	+0.078	+5.106	.003	.008	3	2
BLCA	MLLT10P2 →	+0.252	+5.411	<.001	.005	3	2
LUAD	MTCO1P49 →	+0.075	+5.481	<.001	.005	3	2
LUAD	OR7K1P →	+0.051	+6.197	<.001	.001	3	2
BRCA	RNU1-15P →	+0.465	+7.731	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 390 associations by consensus.

RNA5SP346 by PPP1R7 expression — BRCA

Explore this box plot interactively →