PPP1R7

Across TCGA patient cohorts, PPP1R7 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R7-associated genes across cancer lineages are MEK1 and STAT5a. Each is linked with PPP1R7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R7-to-partner and partner-to-PPP1R7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by PPP1R7-low versus PPP1R7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R7→partner) and Y-score (partner→PPP1R7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.396	+2.000	.016	.032	3	2
UCEC	STAT5a →	+0.387	+2.000	.032	.032	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MEK1 by PPP1R7 expression — UCEC

Explore this box plot interactively →