PPP1R7

Across TCGA cell cohorts, PPP1R7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,264 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPP1R7-associated GO terms across cancer lineages are Protein-RNA covalent cross-linking repair, Otolith mineralization, and Thymidine biosynthetic process. Each is linked with PPP1R7 in more than 10 cancer types. Because this analysis shows association rather than direction, both PPP1R7-to-partner and partner-to-PPP1R7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-RNA covalent cross-linking repair grouped by PPP1R7-low versus PPP1R7-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R7→partner) and Y-score (partner→PPP1R7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Protein-RNA covalent cross-linking repair →	+0.112	+0.852	.007	.002	2	11
BREAST	Otolith mineralization →	+0.150	+0.922	.003	.002	3	9
STOMACH	Thymidine biosynthetic process →	+0.189	+0.624	<.001	<.001	3	9
STOMACH	2'-deoxyribonucleoside biosynthetic process →	+0.189	+0.624	<.001	<.001	3	9
STOMACH	Pyrimidine deoxyribonucleoside biosynthetic process →	+0.189	+0.624	<.001	<.001	3	9
CNS	Protein deneddylation →	+0.093	+0.680	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,264 associations by consensus.

Protein-RNA covalent cross-linking repair by PPP1R7 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →