PPP1R3F

Across TCGA patient cohorts, PPP1R3F mutation is significantly associated with the RNA expression of many other genes, with 2,662 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R3F-associated genes across cancer lineages are RPL39P31, SLC25A15P4, and OR10A5. Each is linked with PPP1R3F in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R3F-to-partner and partner-to-PPP1R3F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL39P31 grouped by PPP1R3F-low versus PPP1R3F-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R3F→partner) and Y-score (partner→PPP1R3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RPL39P31 →	+0.210	+5.008	<.001	.004	3	3
OV	SLC25A15P4 →	+0.539	+4.558	<.001	.004	3	3
SCLC	OR10A5 →	+0.096	+4.847	<.001	.009	3	2
UCEC	TRG-AS1 →	+0.282	+2.721	.003	.003	3	2
LGG	OR6S1 →	+0.046	+5.679	<.001	.003	3	2
LGG	RNU6-1162P →	+0.364	+5.760	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,662 associations by consensus.

RPL39P31 by PPP1R3F expression — LIHC

Explore this box plot interactively →