PPP1R3F

Across TCGA pan-cancer cohorts, PPP1R3F RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated PPP1R3F data layer compared with 7 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PPP1R3F RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PPP1R3F expression acts as an unfavorable survival marker, although some lineages such as CHOL and PAAD show a favorable association.

COAD, CHOL, and PAAD are the cancer types where PPP1R3F RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.592	0.728	.002	53	view →
CHOL	OS	Tertile	All	0.918	0.410	.003	52	view →
PAAD	OS	Quartile	All	0.574	0.161	.001	41	view →
BRCA	DFS	Median	II,III,IV	0.925	0.957	.002	32	view →
SKCM	OS	Median	III,IV	0.511	0.210	<.001	30	view →
ACC	DFS	Quartile	III,IV	0.659	0.088	.006	21	view →
LUAD	DFS	Quartile	III,IV	0.344	0.678	.010	20	view →
PRAD	DFS	Median	All	0.639	0.870	<.001	18	view →
KIRC	DFS	Median	IV	0.256	0.627	.004	10	view →
LIHC	OS	Quartile	II,III,IV	0.851	0.584	.011	10	view →
DLBC	OS	Median	All	0.591	1.000	.031	8	view →
KIRP	DFS	Median	IV	0.041	0.621	.019	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

PPP1R3F–COAD (DFS)

Open the COAD breakdown →