PPP1R36

Across TCGA patient cohorts, PPP1R36 mutation is significantly associated with the RNA expression of many other genes, with 880 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R36-associated genes across cancer lineages are ATP6V0D1, CLDND2, and C19orf47. Each is linked with PPP1R36 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R36-to-partner and partner-to-PPP1R36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6V0D1 grouped by PPP1R36-low versus PPP1R36-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R36→partner) and Y-score (partner→PPP1R36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP6V0D1 →	+0.715	+3.828	<.001	<.001	3	2
UCEC	CLDND2 →	+0.418	+1.946	.009	.008	3	2
UCEC	C19orf47 →	+0.343	+3.595	.009	.001	3	2
UCEC	TONSL →	+0.540	+3.501	.008	.002	3	2
UCEC	ZFYVE19 →	+0.442	+2.609	<.001	.006	3	2
UCEC	TRAPPC2L →	+0.463	+2.955	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 880 associations by consensus.

ATP6V0D1 by PPP1R36 expression — UCEC

Explore this box plot interactively →