PPP1R32

Across TCGA cell cohorts, PPP1R32 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R32-associated genes across cancer lineages are SPAM1, MYL2, and HRG. Each is linked with PPP1R32 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R32-to-partner and partner-to-PPP1R32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPAM1 grouped by PPP1R32-low versus PPP1R32-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R32→partner) and Y-score (partner→PPP1R32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SPAM1 →	+0.007	+4.247	<.001	.004	3	1
BLOOD_Leukemia	MYL2 →	+0.296	+2.982	.003	.007	3	1
BLOOD_Leukemia	HRG →	+0.318	+3.177	<.001	.004	3	1
BLOOD_Leukemia	IFNA8 →	+0.033	+4.124	<.001	<.001	3	1
BLOOD_Leukemia	MAGEB4 →	+0.027	+3.536	<.001	.001	3	1
BLOOD_Leukemia	ABCA12 →	+0.757	+4.015	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

SPAM1 by PPP1R32 expression — BLOOD_Leukemia

Explore this box plot interactively →