PPP1R32

Across TCGA pan-cancer cohorts, PPP1R32 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of PPP1R32’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where PPP1R32 RNA is repressed in tumor relative to normal tissue. In most cancer types PPP1R32 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, LUAD, and COAD are the cancer types where PPP1R32 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPP1R32 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	II,III,IV	−1.857	<.001	8	view →
LUAD	Male	All	−1.276	<.001	8	view →
COAD	All	All	+0.407	<.001	8	view →
KIRP	Male	All	−0.509	<.001	7	view →
BRCA	Female	II,III,IV	−0.386	<.001	4	view →
THCA	All	All	+0.260	<.001	4	view →
UCEC	All	All	−0.976	.015	2	view →
KIRC	Female	All	+0.261	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

PPP1R32–LUSC

Open the LUSC breakdown →