PPP1R2C

Across TCGA patient cohorts, PPP1R2C RNA expression is significantly associated with the go_rna of many other GO terms, with 6,023 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPP1R2C-associated GO terms across cancer lineages are Positive regulation of lymphocyte differentiation, Negative regulation of immune response, and Granzyme-mediated programmed cell death signaling pathway. Each is linked with PPP1R2C in more than 11 cancer types. Because this analysis shows association rather than direction, both PPP1R2C-to-partner and partner-to-PPP1R2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of lymphocyte differentiation grouped by PPP1R2C-low versus PPP1R2C-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R2C→partner) and Y-score (partner→PPP1R2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of lymphocyte differentiation →	+0.075	+0.056	<.001	<.001	3	12
STAD	Negative regulation of immune response →	+0.070	+0.066	<.001	<.001	3	12
TGCT	Granzyme-mediated programmed cell death signaling pathway →	+0.114	+1.228	<.001	<.001	3	11
STAD	Regulation of leukocyte migration →	+0.060	+0.083	<.001	<.001	3	11
STAD	Response to type II interferon →	+0.076	+0.051	<.001	<.001	3	11
STAD	Response to tumor necrosis factor →	+0.063	+0.100	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,023 associations by consensus.

Positive regulation of lymphocyte differentiation by PPP1R2C expression — STAD

Explore this box plot interactively →