PPP1R2C

Across TCGA pan-cancer cohorts, PPP1R2C RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of PPP1R2C’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where PPP1R2C RNA is repressed in tumor relative to normal tissue. In most cancer types PPP1R2C is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

THCA and UCEC are the cancer types where PPP1R2C tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPP1R2C RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.106	.019	4	view →
UCEC	All	All	−0.099	.016	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

PPP1R2C–THCA

Open the THCA breakdown →