PPP1R2C

Across TCGA patient cohorts, PPP1R2C protein abundance is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPP1R2C-associated genes across cancer lineages are TRIM40, MIR1258, and RPL31P59. Each is linked with PPP1R2C in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R2C-to-partner and partner-to-PPP1R2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R2C versus TRIM40 in LSCC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R2C→partner) and Y-score (partner→PPP1R2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIM40 →	+0.043	+2.169	<.001	.008	3	1
LSCC	MIR1258 →	+1.023	+2.169	<.001	.008	3	1
LSCC	RPL31P59 →	+0.293	+2.169	<.001	.008	3	1
LSCC	RNA5SP384 →	+0.876	+1.151	.005	.003	3	1
LSCC	LINC02210-CRHR1 →	+0.036	+2.169	<.001	.008	3	1
LSCC	OPCML-IT1 →	+0.113	+2.169	.008	.008	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

PPP1R2C vs TRIM40 — LSCC

Explore this scatter interactively →