PPP1R2C

Across TCGA patient cohorts, PPP1R2C mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP1R2C-associated genes across cancer lineages are Mesangial cells, Neutrophils, and Th2 cells. Each is linked with PPP1R2C in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R2C-to-partner and partner-to-PPP1R2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by PPP1R2C-low versus PPP1R2C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R2C→partner) and Y-score (partner→PPP1R2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mesangial cells →	-0.056	-2.983	.005	.036	3	1
UCEC	Neutrophils →	+0.016	+2.974	<.001	<.001	3	1
UCEC	Th2 cells →	+0.367	+3.177	<.001	.010	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Mesangial cells by PPP1R2C expression — UCEC

Explore this box plot interactively →