PPP1R2C

Across TCGA cell cohorts, PPP1R2C RNA expression is significantly associated with the mutation status of many other genes, with 117 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R2C-associated genes across cancer lineages are SCN2A, OSBPL5, and ZNF644. Each is linked with PPP1R2C in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R2C-to-partner and partner-to-PPP1R2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCN2A grouped by PPP1R2C-low versus PPP1R2C-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R2C→partner) and Y-score (partner→PPP1R2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SCN2A →	+2.954	+0.086	.005	.001	3	3
BLOOD_Leukemia	OSBPL5 →	+3.539	+0.115	.002	<.001	3	3
OVARY	ZNF644 →	+4.450	+0.043	.004	<.001	3	2
BLOOD_Leukemia	SLC25A17 →	+4.539	+0.230	.007	<.001	3	2
BLOOD_Leukemia	MSLN →	+4.539	+0.174	<.001	<.001	3	2
LARGE_INTESTINE	TAS1R2 →	+2.510	+0.032	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

SCN2A by PPP1R2C expression — BLOOD_Leukemia

Explore this box plot interactively →