PPP1R1C

Across TCGA cell cohorts, PPP1R1C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,585 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R1C-associated GO terms across cancer lineages are Cellular response to indole-3-methanol, Rho protein signal transduction, and Regulation of actin polymerization or depolymerization. Each is linked with PPP1R1C in more than 9 cancer types. Because this analysis shows association rather than direction, both PPP1R1C-to-partner and partner-to-PPP1R1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to indole-3-methanol grouped by PPP1R1C-low versus PPP1R1C-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R1C→partner) and Y-score (partner→PPP1R1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cellular response to indole-3-methanol →	+0.175	+1.960	.001	.003	3	10
OESOPHAGUS	Rho protein signal transduction →	+0.159	+2.568	.004	.004	3	9
BREAST	Regulation of actin polymerization or depolymerization →	+0.059	+1.126	.009	.001	3	9
OESOPHAGUS	Response to indole-3-methanol →	+0.187	+2.770	<.001	<.001	3	9
STOMACH	Protein localization to phagophore assembly site →	+0.141	+1.967	<.001	.001	3	9
LUNG_NSCLC_LUAD	Positive regulation of purine nucleotide biosynthetic process →	+0.125	+1.897	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,585 associations by consensus.

Cellular response to indole-3-methanol by PPP1R1C expression — OESOPHAGUS

Explore this box plot interactively →