PPP1R1C

Across TCGA cell cohorts, PPP1R1C mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP1R1C-associated genes across cancer lineages are TRARG1. Each is linked with PPP1R1C in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R1C-to-partner and partner-to-PPP1R1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRARG1 grouped by PPP1R1C-low versus PPP1R1C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R1C→partner) and Y-score (partner→PPP1R1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TRARG1 →	+0.034	+4.930	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TRARG1 by PPP1R1C expression — LARGE_INTESTINE

Explore this box plot interactively →