PPP1R1A

Across TCGA patient cohorts, PPP1R1A RNA expression is significantly associated with the protein abundance of many other proteins, with 19,304 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP1R1A-associated proteins across cancer lineages are PPP1R1A_S67, PLIN1_S382, and PPP1R12B. Each is linked with PPP1R1A in more than 9 cancer types. Because this analysis shows association rather than direction, both PPP1R1A-to-partner and partner-to-PPP1R1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R1A versus PPP1R1A_S67 in BRCA, with a Pearson correlation of 0.86.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R1A→partner) and Y-score (partner→PPP1R1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPP1R1A_S67 →	+1.792	+2.184	<.001	<.001	3	10
COAD	PLIN1_S382 →	+1.720	+0.391	<.001	<.001	3	5
HNSC	PPP1R12B →	+0.652	+0.718	<.001	<.001	3	5
GBM	ZC3H14 →	-0.228	-0.659	.003	.001	3	5
CCRCC	NEFL →	+1.521	+1.498	<.001	<.001	3	5
OV	LIPE →	+1.170	+1.004	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,304 associations by consensus.

PPP1R1A vs PPP1R1A_S67 — BRCA

Explore this scatter interactively →