PPP1R16A

Across TCGA cell cohorts, PPP1R16A mutation is significantly associated with the mutation status of many other genes, with 3,238 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R16A-associated genes across cancer lineages are MEX3D, FES, and BRF1. Each is linked with PPP1R16A in more than 3 cancer types. Because this analysis shows association rather than direction, both PPP1R16A-to-partner and partner-to-PPP1R16A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEX3D grouped by PPP1R16A-low versus PPP1R16A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R16A→partner) and Y-score (partner→PPP1R16A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MEX3D →	+4.247	+3.560	.002	.002	1	4
OVARY	FES →	+4.217	+4.217	.001	.001	1	4
BLOOD_Leukemia	BRF1 →	+3.662	+3.523	<.001	<.001	1	4
BLOOD_Leukemia	AVPR1B →	+3.662	+3.285	.004	.004	1	4
OVARY	ZFYVE26 →	+3.217	+3.684	.006	.006	1	4
OVARY	TAF3 →	+4.217	+4.217	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,238 associations by consensus.

MEX3D by PPP1R16A expression — BLOOD_Leukemia

Explore this box plot interactively →