PPP1R13L

Across TCGA cell cohorts, PPP1R13L mutation is significantly associated with the RNA expression of many other genes, with 187 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PPP1R13L-associated genes across cancer lineages are EBF2, TPRX1, and REG3G. Each is linked with PPP1R13L in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP1R13L-to-partner and partner-to-PPP1R13L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EBF2 grouped by PPP1R13L-low versus PPP1R13L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R13L→partner) and Y-score (partner→PPP1R13L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EBF2 →	+0.220	+3.814	<.001	.002	3	3
BLOOD_Lymphoma	TPRX1 →	+0.006	+5.209	<.001	.005	3	2
BLOOD_Myeloma	REG3G →	+0.049	+4.321	<.001	<.001	3	1
BLOOD_Myeloma	PRR23A →	+0.047	+3.285	.003	.009	3	1
SOFT_TISSUE	OR7E24 →	+0.029	+5.369	<.001	.004	3	1
SOFT_TISSUE	KRTAP5-4 →	+0.032	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 187 associations by consensus.

EBF2 by PPP1R13L expression — BLOOD_Leukemia

Explore this box plot interactively →