PPP1R13L

Across TCGA pan-cancer cohorts, PPP1R13L RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of PPP1R13L’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PPP1R13L RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PPP1R13L is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, KIRC, and THCA are the cancer types where PPP1R13L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PPP1R13L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	IV	+1.934	<.001	11	view →
KIRC	Male	All	+1.476	<.001	11	view →
THCA	Male	III,IV	+0.988	<.001	10	view →
LIHC	Female	III,IV	+1.295	<.001	9	view →
BLCA	Male	III,IV	+2.351	.012	8	view →
LUSC	Male	II,III,IV	+1.221	<.001	8	view →
KIRP	Male	II,III,IV	+0.942	.003	8	view →
READ	All	III,IV	+1.609	.003	7	view →
KICH	Male	All	−1.731	<.001	6	view →
UCEC	All	All	+1.117	<.001	6	view →
HNSC	All	All	+0.600	.003	6	view →
CHOL	Female	All	+3.646	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

PPP1R13L–COAD

Open the COAD breakdown →