PPM1K-DT

Across TCGA patient cohorts, PPM1K-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,964 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPM1K-DT-associated GO terms across cancer lineages are Negative regulation of viral process, Regulation of actin filament organization, and Regulation by virus of viral protein levels in host cell. Each is linked with PPM1K-DT in more than 17 cancer types. Because this analysis shows association rather than direction, both PPM1K-DT-to-partner and partner-to-PPM1K-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of viral process grouped by PPM1K-DT-low versus PPM1K-DT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1K-DT→partner) and Y-score (partner→PPM1K-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of viral process →	+0.063	+0.167	<.001	<.001	3	18
STAD	Regulation of actin filament organization →	+0.059	+0.200	<.001	<.001	3	15
STAD	Regulation by virus of viral protein levels in host cell →	+0.066	+0.160	<.001	<.001	3	15
STAD	Regulation of viral genome replication →	+0.064	+0.137	<.001	<.001	3	15
STAD	Regulation of pattern recognition receptor signaling pathway →	+0.050	+0.159	<.001	<.001	3	15
STAD	TORC1 signaling →	+0.067	+0.163	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,964 associations by consensus.

Negative regulation of viral process by PPM1K-DT expression — STAD

Explore this box plot interactively →