PPM1J

Across TCGA patient cohorts, PPM1J RNA expression is significantly associated with the protein abundance of many other proteins, with 11,110 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPM1J-associated proteins across cancer lineages are PPM1J_S76, NRBP2, and STUB1. Each is linked with PPM1J in more than 7 cancer types. Because this analysis shows association rather than direction, both PPM1J-to-partner and partner-to-PPM1J results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPM1J versus PPM1J_S76 in BRCA, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1J→partner) and Y-score (partner→PPM1J) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPM1J_S76 →	+1.236	+1.497	<.001	<.001	3	8
OV	NRBP2 →	+0.463	+0.601	<.001	<.001	3	4
BRCA	STUB1 →	+0.397	+0.904	<.001	<.001	3	4
BRCA	GAMT →	+0.716	+1.247	<.001	<.001	3	4
GBM	L3MBTL3 →	-0.424	-0.444	.001	<.001	3	4
GBM	SDC4 →	+0.656	+0.438	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,110 associations by consensus.

PPM1J vs PPM1J_S76 — BRCA

Explore this scatter interactively →