PPM1H

Across TCGA patient cohorts, PPM1H protein abundance is significantly associated with the RNA expression of many other genes, with 11,589 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPM1H-associated genes across cancer lineages are GAPDHP44, RPL32P26, and MANSC1. Each is linked with PPM1H in more than 6 cancer types. Because this analysis shows association rather than direction, both PPM1H-to-partner and partner-to-PPM1H results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPM1H versus GAPDHP44 in UCEC, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1H→partner) and Y-score (partner→PPM1H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDHP44 →	+1.075	+0.668	<.001	<.001	3	7
UCEC	RPL32P26 →	+1.084	+0.681	<.001	<.001	3	7
UCEC	MANSC1 →	+0.863	+0.810	<.001	<.001	3	6
HNSC	CCSER1 →	+1.382	+0.687	<.001	<.001	3	6
UCEC	ELAPOR1 →	+1.467	+0.454	<.001	<.001	3	5
GBM	C1orf115 →	+1.163	+0.690	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,589 associations by consensus.

PPM1H vs GAPDHP44 — UCEC

Explore this scatter interactively →