PPM1H

Across TCGA cell cohorts, PPM1H RNA expression is significantly associated with the go_rna of many other GO terms, with 4,624 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPM1H-associated GO terms across cancer lineages are Regulation of myoblast fusion, Aerobic respiration, and Endosome transport via multivesicular body sorting pathway. Each is linked with PPM1H in more than 10 cancer types. Because this analysis shows association rather than direction, both PPM1H-to-partner and partner-to-PPM1H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by PPM1H-low versus PPM1H-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPM1H→partner) and Y-score (partner→PPM1H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.104	+1.466	<.001	.001	3	11
BLOOD_Myeloma	Aerobic respiration →	+0.077	+1.938	<.001	.003	3	10
BLOOD_Leukemia	Endosome transport via multivesicular body sorting pathway →	+0.058	+1.324	<.001	<.001	3	10
LUNG_SCLC	Alcohol biosynthetic process →	+0.099	+1.714	<.001	<.001	3	9
STOMACH	Vesicle localization →	+0.062	+1.662	<.001	<.001	3	9
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.104	+1.690	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,624 associations by consensus.

Regulation of myoblast fusion by PPM1H expression — OVARY

Explore this box plot interactively →