PPIAP78

Across TCGA patient cohorts, PPIAP78 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,799 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PPIAP78-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, 'de novo' protein folding, and Electron transport chain. Each is linked with PPIAP78 in more than 11 cancer types. Because this analysis shows association rather than direction, both PPIAP78-to-partner and partner-to-PPIAP78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by PPIAP78-low versus PPIAP78-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP78→partner) and Y-score (partner→PPIAP78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial respiratory chain complex assembly →	+0.047	+0.200	<.001	<.001	3	12
STAD	'de novo' protein folding →	+0.042	+0.161	<.001	<.001	3	11
STAD	Electron transport chain →	+0.043	+0.183	<.001	<.001	3	11
STAD	Iron-sulfur cluster assembly →	+0.035	+0.213	<.001	<.001	3	10
STAD	ATP synthesis coupled electron transport →	+0.049	+0.172	<.001	<.001	3	10
ESCA	Oxidative phosphorylation →	+0.052	+0.284	.007	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,799 associations by consensus.

Mitochondrial respiratory chain complex assembly by PPIAP78 expression — STAD

Explore this box plot interactively →